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Thursday, 11 October 2018

Guest lecture on ‘Potential Applications of Stem Cells in Neurological Diseases’ by Dr. Dinesh Upadhya - NGSMIPS

The Department of Pharmaceutics organized a guest lecture on ‘Potential Applications of Stem Cells in Neurological Diseases’ by Dr. Dinesh Upadhya, Assoc. Professor at the Centre for Molecular Neurosciences, KMC Manipal on 6th October 2018 at Paneer Campus, Mangaluru.

Welcoming the guest, staff & students, Dr. C S Shastry, Principal explained that Interdisciplinary science is necessary for dealing with the complex issues of disease management. Use of the best available integrated scientific information must be embraced and supported at all levels of agencies, especially those that deal with healthcare and education. At an academic level rarely has “Stem Cell Research” been defined, its importance explained, or guidance provided on how to translate and then implement the associated research results in novel methods of disease management. Different scientific disciplines need to come together to address the complex issues related to healthcare and to provide sustained therapy.

Dr. Dinesh Upadhya, through his thoroughly educative and appealing presentation, caught the attention of the students as he explained the applications Totipotent, Pluripotent and Multipotent Stem Cells. Many stem cell therapeutics exist, but most are at experimental stages and in Clinical Trial Stages. It has found its major applications in neurological diseases due to the inability of neurons to regenerate itself after damage. Stem cell therapies have demonstrated significant results in the treatment of drug-resistant epilepsy. As of now ‘Hematopoietic Stem Cells’ (HSCs) are the only ones approved for therapeutic use. He also discussed ethical concerns regarding this powerful technology and spread awareness about false advertisements by some hospitals and websites providing stem cell therapies which are not clinically established, to be safe.

There was also a discussion on merging CRISPR/Cas9 technology in stem cell research. CRISPR technology is a simple yet powerful tool for editing genomes. It allows researchers to alter DNA sequences and modify gene function easily. Its many potential applications include correcting genetic defects, treating and preventing the spread of diseases and improving crops. The Principal, Dr. C S Shastry presented Dr. Dinesh with a memento. Mr. Srinivas Hebbar, the faculty in the Department of Pharmaceutics, delivered the Vote of thanks. The lecture session saw active participation of teaching, non-teaching staff members and M.Pharm students.





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